Bioactivity:

K-252c is a staurosporine analog isolated from Nocardiopsis sp. and is a cell-permeable PKC inhibitor (IC50: 2.45 ﾵM). K-252c also inhibits _-lactamase, chymotrypsin, and malate dehydrogenase. K-252c causes apoptosis in human chronic myelogenous leukemia

CAS nr:

85753-43-1

Purity:

98%

Molecular Weight:

311,34

SMILES:

O=C1NCC2=C1C3=C(C4=C2C5=C(N4)C=CC=C5)NC6=C3C=CC=C6

Formula:

C20H13N3O

Pathway:

Cytoskeletal Signaling,Chromatin/Epigenetic

Target:

PKC,PKC