Bioactivity:

PF-05085727 inhibits PDE2A >4,000-fold selectivity over PDE1 and PDE3-11. PF-05085727 is an effective, selective and brain penetrant inhibitor of cGMP-dependent PDE2A (IC50=2 nM) .

CAS nr:

1415637-72-7

Purity:

98%

Molecular Weight:

413,4

SMILES:

CN1C2=NC=NC(N3CCC3)=C2C(C4=C(C5=CC=C(C(F)(F)F)C=C5)N(C)N=C4)=N1

Formula:

C20H18F3N7

Pathway:

Metabolism

Target:

PDE