Bioactivity:

Icariside D2 shows significant cytotoxic activity on the HL-60 cell line with the IC50 value of 9.0 ﾱ 1.0 uM, it induces apoptosis via alteration of expression of apoptosis-related proteins and decreased phosphorylation of AKT in HL-60 cells.

CAS nr:

38954-02-8

Purity:

98%

Molecular Weight:

300,3

SMILES:

OCCc1ccc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1

Formula:

C14H20O7

Pathway:

Cytoskeletal Signaling,PI3K/Akt/mTOR signaling

Target:

Akt,Akt