Bioactivity:

The tyrphostin AG-126 selectively inhibits the phosphorylation of ERK1 (p44) and ERK2 (p42) at 25-50 _M. It blocks the production of TNF-_ in vitro2 and in vivo, attenuating signaling through NF-_B, the induced expression of COX-2 and iNOS, and the inflam

CAS nr:

118409-62-4

Purity:

98%

Molecular Weight:

215,17

SMILES:

C1=CC(=C(C=C1C=C(C#N)C#N)O)[N+](=O)[O-]

Formula:

C10H5N3O3

Pathway:

Neuroscience,Immunology/Inflammation,MAPK

Target:

COX,COX,ERK