Bioactivity:

UNC2541 is a potent and Mer tyrosine kinase (MerTK)-specific inhibitor. It also binds in the MerTK ATP pocket (IC50: 4.4 nM). UNC2541 inhibits phosphorylated MerTK (pMerTK; EC50, 510 nM).

CAS nr:

1612782-86-1

Purity:

98%

Molecular Weight:

471,57

SMILES:

C1CCCNC2=NC=C(C(=N2)NCCCC[C@@H](C(=O)NCC1)N)C(=O)NCC3=CC=C(C=C3)F

Formula:

C24H34FN7O2

Pathway:

Tyrosine Kinase/Adaptors,Others,Angiogenesis,Tyrosine Kinase/Adaptors

Target:

TAM Receptor,Others,FLT,FLT