INCB3344 TQ0103
Specifications
| 1mg/5mg/10mg/25mg/50mg/100mg |
Bioactivity:
INCB3344 is an effective, specific and orally bioavailable CCR2 antagonist with IC50 values of 9.5 nM (mCCR2) and 5.1 nM (hCCR2) in binding antagonism and 7.8 nM (mCCR2) and in 3.8 nM (hCCR2) antagonism of chemotaxis activity.
CAS nr:
1262238-11-8
Purity:
98%
Molecular Weight:
577,24
SMILES:
CCOC1CN(CC1NC(=O)CNC(=O)C2=CC(=CC=C2)C(F)(F)F)C3CCC(CC3)(C4=CC5=C(C=C4)OCO5)O
Formula:
C29H34F3N3O6
Pathway:
Microbiology/Virology,Immunology/Inflammation
Target:
CCR,CCR
