Bioactivity:

Apremilast D5 (CC-10004 D5) is a deuterium-labeled Apremilast. Apremilast is an orally available inhibitor of PDE-4 (IC50: 74 nM). Apremilast inhibits TNF-_ release by lipopolysaccharide (IC50: 104 nM).

CAS nr:

1258597-47-5

Purity:

98%

Molecular Weight:

465,53

SMILES:

CC(NC1=CC=CC(C(N2[C@@H](C3=CC=C(OC)C(OC([2H])([2H])C([2H])([2H])[2H])=C3)CS(=O)(C)=O)=O)=C1C2=O)=O

Formula:

C22H19D5N2O7S

Pathway:

Metabolism,Apoptosis

Target:

PDE,TNF