Bioactivity:

DDD85646 is a T. brucei N-myristoyltransferase (TbNMT) (apparent Ki = 1.44 nM) . DDD85646 has potent activity against the enzyme (IC(50) = 2 nM) and T. brucei (EC(50) = 2 nM) in culture. DDD85646 has good oral pharmacokinetics and cures rodent models of p

CAS nr:

1215010-55-1

Purity:

98%

Molecular Weight:

495,42

SMILES:

O=S(C1=C(Cl)C=C(C2=CC(N3CCNCC3)=NC=C2)C=C1Cl)(NC4=C(C)N(C)N=C4C)=O

Formula:

C21H24Cl2N6O2S

Pathway:

Microbiology/Virology

Target:

Parasite