Bioactivity:

Ivosidenib is an orally available inhibitor of isocitrate dehydrogenase type 1 (IDH1), with potential antineoplastic activity. Ivosidenib specifically inhibits a mutated form of IDH1 in the cytoplasm, which inhibits the formation of the oncometabolite, 2-

CAS nr:

1448347-49-6

Purity:

98%

Molecular Weight:

582,97

SMILES:

Fc1cncc(c1)N([C@H](C(=O)NC1CC(F)(F)C1)c1ccccc1Cl)C(=O)[C@@H]1CCC(=O)N1c1cc(ccn1)C#N

Formula:

C28H22ClF3N6O3

Pathway:

Metabolism,Metabolism

Target:

Isocitrate Dehydrogenase (IDH),Dehydrogenase