Bioactivity:

BX471 hydrochloride (ZK-811752 hydrochloride) is a potent, selective non-peptide CCR1 antagonist (Ki: 1 nM for human CCR1). It shows 250-fold selectivity for CCR1 over CCR2, CCR5, and CXCR4.

CAS nr:

288262-96-4

Purity:

98%

Molecular Weight:

471,35

SMILES:

O=C(N)NC1=CC(Cl)=CC=C1OCC(N2[C@H](C)CN(CC3=CC=C(F)C=C3)CC2)=O.[H]Cl

Formula:

C21H25Cl2FN4O3

Pathway:

Others

Target:

Others