Bioactivity:

LT052 shows nanomolar BRD4 BD1 potency and 138-fold selectivity over BRD4 BD2. LT052 has inhibitory activities against BRPF1b (IC50=567.5 nM). LT052 has anti-inflammatory activity.�LT052 is a highly selective BET BD1 inhibitor.�LT052 displays inhibitory a

CAS nr:

T11887

Purity:

98%

Molecular Weight:

449,48

SMILES:

O=S(C1=CC=CC=C1OC)(NC2=C3N=C(N4C=C(C)N=C4)C=C5C3=C(N(C)C5=O)C=C2)=O

Formula:

C22H19N5O4S

Pathway:

Chromatin/Epigenetic

Target:

Epigenetic Reader Domain