Bioactivity:

JNJ-64619178 is a selective, orally active, and pseudo-irreversible inhibitor of protein arginine methyltransferase 5 (IC50: 0.14 nM). It has effective activity In lung cancer.

CAS nr:

2086772-26-9

Purity:

98%

Molecular Weight:

483,36

SMILES:

Nc1c(ccn2[C@H](C[C@H](CCc3ccc(cc(c(N)n4)Br)c4c3)[C@H]3O)[C@@H]3O)c2ncn1

Formula:

C22H23BrN6O2

Pathway:

Chromatin/Epigenetic

Target:

Histone Methyltransferase