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(ﾱ)-10-Hydroxycamptothecin T1521

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Specifications

size	1mg/5mg/10mg/25mg/50mg/100mg

Bioactivity:

(ﾱ)-10-Hydroxycamptothecin is an alkaloid isolated from the stem wood of the Chinese tree, Camptotheca acuminata. This compound selectively inhibits the nuclear enzyme DNA topoisomerase, type I. Several semisynthetic analogs of camptothecin have demonstrated antitumor activity.

CAS nr:

64439-81-2

Purity:

98%

Molecular Weight:

364,35

SMILES:

CCC1(c2c(COC1=O)c(=O)n1Cc3c(c1c2)nc1ccc(cc1c3)O)O

Formula:

C20H16N2O5

Pathway:

DNA Damage/DNA Repair

Target:

Topoisomerase