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Bioactivity:
Entospletinib _IC50= 7.7 nM_is a specific Syk inhibitor, which is orally bioavailable.
CAS nr:
1229208-44-9
Purity:
98%
Molecular Weight:
411,47
SMILES:
C1CN(CCO1)c1ccc(Nc2nc(cn3ccnc23)c2ccc3cn[nH]c3c2)cc1
Formula:
C23H21N7O
Pathway:
Angiogenesis,Tyrosine Kinase/Adaptors
Target:
Syk,Syk