Bioactivity:

Daphnetin, a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 _M), PKA (IC50: 9.33 _M), and PKC (IC50: 25.01 _M), also exhibit anti-oxidant and anti-inflammatory activities.

CAS nr:

486-35-1

Purity:

98%

Molecular Weight:

178,14

SMILES:

c1cc(c(c2c1ccc(=O)o2)O)O

Formula:

C9H6O4

Pathway:

Tyrosine Kinase/Adaptors,Microbiology/Virology,JAK/STAT signaling,Autophagy,Tyrosine Kinase/Adaptors,Angiogenesis,Cytoskeletal Signaling,Chromatin/Epigenetic

Target:

PKA,Parasite,EGFR,Autophagy,EGFR,EGFR,PKC,PKC