Bioactivity:

RAF mutant-IN-1 is an inhibitor of RAF kinase(IC50 values of 21 nM, 30 nM and 392 nM for C-RAF 340D/Y341D, B-RAFV600E and B-RAFWT, respectively).

CAS nr:

2340020-82-6

Purity:

98%

Molecular Weight:

567,85

SMILES:

O=C(C1=CSC2=C(N)N=CN=C21)NC3=C(C)C=CC4=C3C=CN=C4NC5=CC=C(O)C(Cl)=C5F.[H]Cl.[H]Cl

Formula:

C23H18Cl3FN6O2S

Pathway:

Others

Target:

Others