Bioactivity:

FR183998 free base is a potent Na+/H+-exchange inhibitor, with IC50s of 0.3 nM, 3.1 nM and 6.5 nM by measurement of pHi change in rat lymphocytes, rat and human platelets, respectively.

CAS nr:

239440-20-1

Purity:

98%

Molecular Weight:

428,34

SMILES:

O=C(C1=CC(C2=C(Cl)SC(Cl)=C2)=CC(C(NCCN(C)C)=O)=C1)NC(N)=N

Formula:

C17H19Cl2N5O2S

Pathway:

Others

Target:

Others