PTC-028 T16680
Specifications
| 1mg/5mg/10mg/25mg/50mg/100mg |
Bioactivity:
PTC-028 selectively suppresses cancer cells whereas normal cells remain unaffected. PTC-028 is an orally bioavailable inhibitor of stem cell factor BMI-1 in ovarian cancer. The depletion of BMI-1 by PTC-028 causes caspase-mediated apoptosis.
CAS nr:
1782970-28-8
Purity:
98%
Molecular Weight:
405,32
SMILES:
Cc1nc2cc(F)c(F)cc2n1-c1cncc(Nc2ccc(cc2)C(F)(F)F)n1
Formula:
C19H12F5N5
Pathway:
DNA Damage/DNA Repair,Cell Cycle/Checkpoint,Apoptosis
Target:
BMI-1,BMI-1,Apoptosis
