Bioactivity:

Imarikiren is a potent, selective and orally active direct renin inhibitor. TAK-272 shows potent inhibitory activity against human renin (IC50 = 2.1 nM) in hPRA assay and excellent selectivity against other aspartic proteases, such as cathepsin D (IC50 >

CAS nr:

1202269-24-6

Purity:

98%

Molecular Weight:

536,11

SMILES:

O=C(C1=NC2=CC=CC=C2N1CCCCOC)N(CC(C)C)[C@@H]3CNC[C@H](C(N4CCOCC4)=O)C3.[H]Cl

Formula:

C27H42ClN5O4

Pathway:

Target: