Bioactivity:

ITI214 is a picomolar PDE1 inhibitor with excellent selectivity against other PDE family members and against a panel of enzymes, receptors, transporters, and ion channels, exhibits potent PDE1 inhibitory activity (Ki = 58 pM).

CAS nr:

1642303-38-5

Purity:

98%

Molecular Weight:

605,56

SMILES:

O=C(C1=C(NC2=CC=CC=C2)N(CC3=CC=C(C4=NC(F)=CC=C4)C=C3)N=C1N56)N(C)C5=N[C@@]7([H])[C@]6([H])CCC7.O=P(O)(O)O

Formula:

C29H29FN7O5P

Pathway:

Metabolism

Target:

PDE