Bioactivity:

(R)-BMS-816336 is a potent and orally active inhibitor of human, mouse and cynomolgus monkey 11_-hydroxysteroid dehydrogenase type 1 (11_-HSD1) enzyme(IC50s of 14.5 nM, 50.3 nM and 16 nM, respectively ).

CAS nr:

1009583-83-8

Purity:

98%

Molecular Weight:

341,44

SMILES:

O[C@H]1[C@H]2C[C@@H]3[C@@](C4=CC=CC=C4)(CC(N5CC(O)C5)=O)[C@@H](C[C@H]1C3)C2

Formula:

C21H27NO3

Pathway:

Metabolism

Target:

Dehydrogenase