Bioactivity:

PF-05105679 has the potential for cold-related pain. PF-05105679 is an orally active and selective TRPM8 antagonist (IC50: 103 nM).

CAS nr:

1398583-31-7

Purity:

98%

Molecular Weight:

428,45

SMILES:

O=C(O)C1=CC=CC(CN([C@@H](C2=CC=C(F)C=C2)C)C(C3=CC4=CC=CC=C4N=C3)=O)=C1

Formula:

C26H21FN2O3

Pathway:

Membrane transporter/Ion channel

Target:

TRP/TRPV Channel