Bioactivity:

TPN171 is a selective and oral bioavailable phosphodiesterase type 5 (PDE5) inhibitor (IC50: 0.62 nM), which has the potential for the treatment of pulmonary arterial hypertension (PAH).

CAS nr:

1229018-87-4

Purity:

98%

Molecular Weight:

441,57

SMILES:

CCCOC1=C(C2=NC(CC)=C(CC)C(N2)=O)C=C(NC(CN3CCN(C)CC3)=O)C=C1

Formula:

C24H35N5O3

Pathway:

Metabolism

Target:

PDE