Bioactivity:

Phthalazinone pyrazole is potent, selective, and orally bioavailable inhibitor of Aurora-A kinase. Aurora-A is overexpressed in a variety of tumor types and displays oncogenic activity.

CAS nr:

880487-62-7

Purity:

98%

Molecular Weight:

317,34

SMILES:

CC1=CC(NC(C2=C3C=CC=C2)=NN(C4=CC=CC=C4)C3=O)=NN1

Formula:

C18H15N5O

Pathway:

Chromatin/Epigenetic,Cell Cycle/Checkpoint

Target:

Aurora Kinase,Aurora Kinase