Bioactivity:

UT-34 is a selective and orally active antagonist of second-generation pan-androgen receptor (AR) and degrader(IC50s of 211.7 nM, 262.4 nM and 215.7 nM for wild-type, F876L and W741L AR, respectively), and has anti-prostate cancer efficacy.

CAS nr:

2168525-92-4

Purity:

98%

Molecular Weight:

356,27

SMILES:

C[C@](O)(Cn1cc(F)cn1)C(=O)Nc1ccc(C#N)c(c1)C(F)(F)F

Formula:

C15H12F4N4O2

Pathway:

Endocrinology/Hormones

Target:

Androgen Receptor