Bioactivity:

Ipatasertib dihydrochloride is a highly selective and ATP-competitive inhibitor of pan-Akt (IC50s: 5, 18, and 8 nM for Akt1, Akt2, and Akt3, respectively).

CAS nr:

1396257-94-5

Purity:

98%

Molecular Weight:

530,92

SMILES:

ClC1=CC=C([C@@H](CNC(C)C)C(N2CCN(C3=C([C@H](C)C[C@H]4O)C4=NC=N3)CC2)=O)C=C1.[H]Cl.[H]Cl

Formula:

C24H34Cl3N5O2

Pathway:

Tyrosine Kinase/Adaptors,PI3K/Akt/mTOR signaling,Cytoskeletal Signaling

Target:

PKA,Akt,Akt