Bioactivity:

SW155246 is a potent and selective inhibitor of DNMT1 (DNA methyltransferase 1; IC50 of 1.2 _M). SW155246 induces re-expression of the tumor suppressor geneRASSF1 in A549 cells.

CAS nr:

420092-79-1

Purity:

98%

Molecular Weight:

378,79

SMILES:

C1=CC=C2C(=C1)C(=CC=C2O)NS(=O)(=O)C3=CC(=C(C=C3)Cl)[N+](=O)[O-]

Formula:

C16H11ClN2O5S

Pathway:

Chromatin/Epigenetic

Target:

DNA Methyltransferase