Bioactivity:

S-methyl DM1 is a thiomethyl derivative of Maytansine. S-methyl DM1 binds to tubulin(Kd of 0.93 _M) and inhibts microtubule polymerization.

CAS nr:

912569-84-7

Purity:

98%

Molecular Weight:

752,31

SMILES:

C[C@]1([C@@](CC(N(C2=CC3=CC(OC)=C2Cl)C)=O)([H])OC([C@H](C)N(C)C(CCSC)=O)=O)[C@H]([C@@H]([C@](OC4=O)([H])C[C@]([C@](/C=C/C=C(C)/C3)([H])OC)(N4)O)C)O1

Formula:

C36H50ClN3O10S

Pathway:

Cytoskeletal Signaling

Target:

Microtubule Associated