Bioactivity:

EPZ004777 hydrochloride is a potent, selective DOT1L inhibitor with IC50 of 0.4 nM.

CAS nr:

1380316-03-9

Purity:

98%

Molecular Weight:

576,13

SMILES:

CC(C)N(CCCNC(=O)NC1=CC=C(C=C1)C(C)(C)C)C[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=CC4=C3N=CN=C4N)O)O.Cl

Formula:

C28H42ClN7O4

Pathway:

Apoptosis,Chromatin/Epigenetic

Target:

Apoptosis,Histone Methyltransferase