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Bioactivity:
Lerociclib (G1T38) is a potent and selective inhibitor of CDK4/6, with IC50s of 2nM, 1 nM for CDK6/CyclinD3�and CDK4/CyclinD1, respectively.
CAS nr:
1628256-23-4
Purity:
98%
Molecular Weight:
474,6
SMILES:
O=C1NCC2(N3C1=CC4=CN=C(NC5=NC=C(N6CCN(C(C)C)CC6)C=C5)N=C43)CCCCC2
Formula:
C26H34N8O
Pathway:
Cell Cycle/Checkpoint
Target:
CDK