TargetMol Chemicals

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BMS 599626 2HCl (873837-23-1(HCl)) T5398

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Specifications

size	1mg/5mg/10mg/25mg/50mg/100mg

Bioactivity:

BMS-599626 (AC480) is a selective inhibitor of HER1 and HER2 (IC50s: 20 nM and 30 nM), ~8-fold less potent to HER4, >100-fold to Lck, VEGFR2, c-Kit, MET, etc.

CAS nr:

T5398

Purity:

98%

Molecular Weight:

603,47

SMILES:

Cl.Cl.Cc1c(NC(=O)OC[C@@H]2COCCN2)cn2ncnc(Nc3ccc4n(Cc5cccc(F)c5)ncc4c3)c12

Formula:

C27H29Cl2FN8O3

Pathway:

Tyrosine Kinase/Adaptors,Angiogenesis,JAK/STAT signaling

Target:

HER,HER,HER