Bioactivity:

Deltonin has an inhibition of ERK1/2 and AKT activation. Deltonin shows cytotoxicity against human HepG2 cells (IC50: 7.66 _M), mouse C26 cells (IC50: 1.22 _M), and human MDA-MB-231 cells (IC50: 1.58 _M).

CAS nr:

55659-75-1

Purity:

98%

Molecular Weight:

885,05

SMILES:

O[C@@H]9[C@H](O)[C@@H](O)[C@H](C)O[C@H]9O[C@@H]8[C@@H](O)[C@H](O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)[C@@H](CO)O[C@H]8O[C@@H]6CC7=CC[C@@H]3[C@H](CC[C@]4(C)[C@H]5[C@H](C)[C@@]2(CC[C@@H](C)CO2)O[C@H]5C[C@@H]34)[C@@]7(C)CC6

Formula:

C45H72O17

Pathway:

Metabolism,Others,PI3K/Akt/mTOR signaling,Cytoskeletal Signaling,MAPK

Target:

Endogenous Metabolite,Others,Akt,Akt,ERK