Bioactivity:

Ixabepilone is an orally bioavailable microtubule inhibitor. It binds to tubulin and promotes tubulin polymerization and microtubule stabilization, thereby arresting cells in the G2-M phase of the cell cycle and inducing tumor cell apoptosis.

CAS nr:

219989-84-1

Purity:

98%

Molecular Weight:

506,7

SMILES:

C[C@H]1CCC[C@@]2([C@@H](O2)C[C@H](NC(=O)C[C@@H](C(C(=O)[C@@H]([C@H]1O)C)(C)C)O)/C(=C/C3=CSC(=N3)C)/C)C

Formula:

C27H42N2O5S

Pathway:

Cytoskeletal Signaling,Apoptosis

Target:

Microtubule Associated,Apoptosis