Bioactivity:

PF-04447943 is an effective inhibitor of human recombinant PDE9A (IC50=12 nM). It has >78-fold selectivity, compared to other PDE family members (IC50>1000 nM).

CAS nr:

1082744-20-4

Purity:

98%

Molecular Weight:

395,46

SMILES:

O=C1C2=C(N(C3CCOCC3)N=C2)N=C([C@@H]4CN(CC5=NC=CC=N5)C[C@H]4C)N1

Formula:

C20H25N7O2

Pathway:

Metabolism

Target:

PDE