Bioactivity:

Zamicastat is an inhibitor of dopamine _-hydroxylase (DBH), and is also a concentration-dependent dual inhibitor of P-gp and BCRP(IC50 values of 73.8__M and 17.0__M, respectively).

CAS nr:

1080028-80-3

Purity:

98%

Molecular Weight:

401,47

SMILES:

Fc(cc1F)cc(C2)c1OC[C@@H]2N(C(CCNCc1ccccc1)=CN1)C1=S

Formula:

C21H21F2N3OS

Pathway:

Metabolism,Membrane transporter/Ion channel,Neuroscience,Membrane transporter/Ion channel

Target:

Hydroxylase,BCRP,P-gp,P-gp