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Bioactivity:
GSK461364(Ki=2.2 nM) inhibits purified Plk1 .The specificity of GSK461364 for Plk1 is more than 1000-fold over Plk2/3.
CAS nr:
929095-18-1
Purity:
98%
Molecular Weight:
543,6
SMILES:
c1(c(cc(s1)n1cnc2c1cc(cc2)CN1CCN(CC1)C)O[C@H](C)c1c(cccc1)C(F)(F)F)C(=O)N
Formula:
C27H28F3N5O2S
Pathway:
Cell Cycle/Checkpoint
Target:
PLK