Bioactivity:

Pancuronium dibromide, a competitive AChR antagonist (IC50 = 5.5 nM), acts as a skeletal muscle relaxant. Pancuronium dibromide blocking neuromuscular transmission is achieved by competing with acetylcholine for receptor sites on the motor end-plate.

CAS nr:

15500-66-0

Purity:

98%

Molecular Weight:

732,67

SMILES:

CC(=O)O[C@H]1C[C@@H]2CC[C@@H]3[C@@H]([C@]2(C[C@@H]1[N+]1(CCCCC1)C)C)CC[C@]1([C@H]3C[C@@H]([C@@H]1OC(=O)C)[N+]1(CCCCC1)C)C.[Br-].[Br-]

Formula:

C35H60Br2N2O4

Pathway:

Neuroscience

Target:

AChR