Bioactivity:

BMS-1001 hydrochloride is an orally active inhibitor of human PD-1/PD-L1 immune checkpoint with low-toxicity in cells.BMS-1001 alleviates the inhibitory effect of the soluble PD-L1 on the T-cell receptor-mediated activation of T-lymphocytes.�BMS-1001 is c

CAS nr:

2113650-04-5

Purity:

98%

Molecular Weight:

631,11

SMILES:

Cl.Cc1cc(CN[C@H](CO)C(O)=O)c(OCc2cccc(c2)C#N)cc1OCc1cccc(c1C)-c1ccc2OCCOc2c1

Formula:

C35H35ClN2O7

Pathway:

Cell Cycle/Checkpoint,Apoptosis,Immunology/Inflammation

Target:

PD-1/PD-L1,PD-1/PD-L1,PD-1/PD-L1