Bioactivity:

Mavorixafor (AMD-070) is a selective and orally available CXCR4 antagonist (IC50: 13 nM against CXCR4 125I-SDF binding) and also inhibits the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells and PBMCs (IC50: 1 and 9 nM).

CAS nr:

558447-26-0

Purity:

98%

Molecular Weight:

349,48

SMILES:

NCCCCN(Cc1nc(cccc2)c2[nH]1)[C@@H]1c2ncccc2CCC1

Formula:

C21H27N5

Pathway:

GPCR/G Protein,Autophagy,Immunology/Inflammation

Target:

CXCR,CXCR,CXCR