Sonidegib T1926
Specifications
| 1mg/5mg/10mg/25mg/50mg/100mg |
Bioactivity:
LDE225 (NVP-LDE225; Erismodegib), a Smoothened (Smo) antagonist, inhibits Hedgehog (Hh) signaling with IC50 of 1.3 nM (mouse) and 2.5 nM (human), respectively.
CAS nr:
956697-53-3
Purity:
98%
Molecular Weight:
485,5
SMILES:
C[C@H]1CN(C[C@@H](C)O1)c1ccc(NC(=O)c2cccc(-c3ccc(OC(F)(F)F)cc3)c2C)cn1
Formula:
C26H26F3N3O3
Pathway:
Stem Cells,GPCR/G Protein,Stem Cells
Target:
Smo,Hedgehog/Smoothened,Hedgehog/Smoothened
