Bioactivity:

VU 0361737 is a specific positive allosteric modulator (PAM) of mGlu4 receptor.The EC50 of VU 0361737 is 240 nM for the human receptors. The EC50 of VU 0361737 is110 nM for rat receptors.It exhibits weak activity at mGlu5 and mGlu8 receptors, and is inact

CAS nr:

1161205-04-4

Purity:

98%

Molecular Weight:

262,69

SMILES:

COc1c(ccc(c1)NC(=O)c1ccccn1)Cl

Formula:

C13H11ClN2O2

Pathway:

Neuroscience

Target:

GluR