Bioactivity:

TGF_RI-IN-1 is an oral active and selective inhibitor of TGF_ receptor type I (TGF_RI) kinase(IC50 values of 2 nM and 7.6 _M for TGF_RI and TGF_RII, respectively ).

CAS nr:

1950628-94-0

Purity:

98%

Molecular Weight:

362,4

SMILES:

CC(NC1=NC=CC(C(N2)=C(C3=NC=C(OC([2H])([2H])[2H])C=C3)C4=C2C=CC=N4)=C1)=O

Formula:

C20H14D3N5O2

Pathway:

Stem Cells

Target:

TGF-beta/Smad