Bioactivity:

Trk-IN-4 is an effective pan-Trk inhibitor in cell-based assays (IC50s: 1.9 nM, 2.6 nM, and 1.1 nM for TrkA, TrkB, and TrkC, respectively).

CAS nr:

1799788-94-5

Purity:

98%

Molecular Weight:

521,46

SMILES:

O=C(N)C1=C(O[C@H]2CCN(C(CC3=CC=C(OC(F)(F)F)C=C3)=O)C[C@H]2F)N=CC(C4=CN(C)C=N4)=C1

Formula:

C24H23F4N5O4

Pathway:

Tyrosine Kinase/Adaptors

Target:

Trk receptor