Bioactivity:

CRT0066854 hydrochloride is an effective selective atypical PKCs inhibitor. CRT0066854 is against full-length (FL) PKC_, PKC_, and ROCK-II kinases with IC50 values of 132 nM, 639 nM, and 620 nM, respectively.

CAS nr:

2250019-91-9

Purity:

98%

Molecular Weight:

452,01

SMILES:

N[C@H](CNC1=NC(C2=CC=NC=C2)=NC3=C1C(CCCC4)=C4S3)CC5=CC=CC=C5.[H]Cl

Formula:

C24H26ClN5S

Pathway:

Cytoskeletal Signaling,Chromatin/Epigenetic

Target:

PKC,PKC