Bioactivity:

R916562 is an orally active and selective Axl/VEGF-R2 inhibitor with IC50s of 136 nM and 24 nM, respectively. R916562 has anti-angiogenesis and anti-metastasis.

CAS nr:

1037798-41-6

Purity:

98%

Molecular Weight:

536,09

SMILES:

NC1=NC(NC(C=C2)=CC=C2N3CCN([C@H]4[C@@H]5CC[C@@H](C5)C4)CC3)=NN1C6=NC(Cl)=NC7=C6SC=C7C

Formula:

C26H30ClN9S

Pathway:

Tyrosine Kinase/Adaptors

Target:

TAM Receptor