Bioactivity:

Tenovin-1 inhibits protein-deacetylating activities of SirT1 and SirT2 and protects against MDM2-mediated p53 degradation, which involves ubiquitination.

CAS nr:

380315-80-0

Purity:

98%

Molecular Weight:

369,48

SMILES:

CC(=O)NC1=CC=C(NC(=S)NC(=O)C2=CC=C(C=C2)C(C)(C)C)C=C1

Formula:

C20H23N3O2S

Pathway:

DNA Damage/DNA Repair,Chromatin/Epigenetic,Apoptosis,Autophagy,Metabolism,Apoptosis

Target:

Sirtuin,Sirtuin,Mdm2,Autophagy,Dehydrogenase,p53