Bioactivity:

BGB-102 is a potent multi-kinase inhibitor against HER2, EGFR, and HER4 (IC50s: 18 nM, 9.6 nM, and 40.3 nM).

CAS nr:

807640-87-5

Purity:

98%

Molecular Weight:

457,36

SMILES:

CN1CCCCCOC(C(OC)=C2)=CC3=C2N=CN/C3=N\C4=CC(Br)=CC=C4C1

Formula:

C22H25BrN4O2

Pathway:

Tyrosine Kinase/Adaptors,Angiogenesis,JAK/STAT signaling,Angiogenesis,JAK/STAT signaling,Tyrosine Kinase/Adaptors

Target:

HER,HER,HER,EGFR,EGFR,EGFR