Necrostatin-1 T1847
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Specifications
| 1mg/5mg/10mg/25mg/50mg/100mg |
Bioactivity:
Necrostatin-1 is a specific RIP1 inhibitor and inhibits TNF-_-induced necroptosis (EC50: 490 nM in Jurkat cells).
CAS nr:
4311-88-0
Purity:
98%
Molecular Weight:
259,33
SMILES:
CN1C(=S)NC(Cc2c[nH]c3ccccc23)C1=O
Formula:
C13H13N3OS
Pathway:
NF-_b,Apoptosis,Metabolism,Autophagy,Cell Cycle/Checkpoint,Apoptosis
Target:
RIP kinase,RIP kinase,Indoleamine 2,3-Dioxygenase (IDO),Autophagy,Ferroptosis,Ferroptosis