Bioactivity:

Supinoxin is an orally active inhibitor of phosphorylated-p68 RNA helicase and a potent first-in-class anti-cancer agent. Supinoxin induces cell apoptosis and inhibits growth of TNBC cancer cell lines (IC50s: ranging from 10 nM to 20 nM).

CAS nr:

888478-45-3

Purity:

98%

Molecular Weight:

441,46

SMILES:

O=C(N1CCN(C2=CC(OC)=CC(OC)=C2)CC1)NC3=NC4=CC(F)=CC=C4N=C3OC

Formula:

C22H24FN5O4

Pathway:

DNA Damage/DNA Repair,Cell Cycle/Checkpoint,Apoptosis

Target:

DNA/RNA Synthesis,DNA/RNA Synthesis,Apoptosis