Bioactivity:

JI051,Anti-cancer activity. is a stabilizer for the Hes1-PHB2 interaction, interacts with a cancer-associated protein chaperone prohibitin 2 (PHB2), induces cell-cycle arrest by inhibiting the Notch downstream effector gene Hes1.

CAS nr:

2234281-75-3

Purity:

98%

Molecular Weight:

364,44

SMILES:

O=C(NCCC1=CC=CC=C1OCC)/C=C/C2=CNC3=C2C=CC=C3OC

Formula:

C22H24N2O3

Pathway:

Others

Target:

Others